December 2012 Newsletter


J. Lewis Research, Inc.


December 2012

The following enrolling studies are featured in this month’s edition of our newsletter:

MMR Vaccine (Ages 12-15 months)

MMR Vaccine (Ages 4-6)

Birth Control (Ages 18-50)

High Cholesterol (Ages 18-80)

9-valent HPV Vaccine (Ages 16-26)

Flu Treatment (Ages 18-70) Must contact site within 48 hours of onset

Meningitis B Vaccine vs. Havrix (Ages 10-26)

Meningitis B Vaccine with TDaP and Menactra (Ages 10-12)

Licensed Hepatitis B Vaccine (Ages 20 and up)

Celiac Disease (Ages 18-75)

Swimmer’s Ear (Ages 6 months and up)

Adolescent Migraine (Ages 12-17)

Our Centerwatch profile

MMR VACCINE- Ages 12 to 15 months

Participating locations: Foothill Family Clinic and Foothill Family Clinic South

MMR vaccine

The MMR vaccine is a “3-in-1” vaccine that protects against measles, mumps, and rubella — all of which are potentially serious diseases of childhood.



The MMR is one of the recommended childhood immunizations. Usually, proof of MMR vaccination is needed to go to school.

  • The first shot is given when the child is 12 to 15 months old. To make sure the child is properly protected, the vaccine must not be given too early.
  • A second MMR shot is given before a child enters school at 4 – 6 years, but may be given at any time after that. Some states require a second MMR before a child starts kindergarten.

For more from this article, please follow the link:

Several vaccinations are recommended for children 12 to 15 months of age.

Our office is conducting a clinical research study comparing an investigational vaccine for Measles/Mumps/Rubella (MMR) with a US-licensed MMR vaccine when given at the same time as the Varicella, Hepatitis A and Pneumococcal disease vaccines.

To qualify for this clinical study, your child must be:

  • 12 to 15 months of age
  • Accompanied by a parent or guardian at each visit
  • Up to date on all current childhood vaccinations

To learn more about this important clinical research study, please call our office today. Our staff is available to provide more detail about this study and answer any questions you may have.

We look forward to hearing from you.

MMR VACCINE- Ages 4 to 6

Participating locations: Jordan River Family Medicine



A clinical research study is evaluating an investigational vaccine to prevent Measles/Mumps/Rubella (MMR) in children

To qualify for this clinical study, your child must be:

  • 4 to 6 years of age
  • Accompanied by a parent or guardian at each study visit
  • Up to date on all current childhood vaccinations

If your child joins this clinical study he/she will receive:

  • MMR vaccination
  • Study-related medical check-ups
  • Payment for the cost of travelling to study visits

If you or someone you know may be interested in participating in this vaccine study, ask your doctor for more information.


Participating locations: Foothill Family Clinic and Jordan River Family Medicine


Seeking a different kind of birth control pill?

Explore your options.

Local doctors are studying a new type of low dose investigational birth control pill. This clinical research study is studying an investigational birth control pill that uses hormones similar to those already in your body. If you’re a sexually active woman between18 and 50 and qualify for this study, you may receive at no cost:

  • Study birth control medication for a year
  • Study-related care from a local doctor
  • Possible reimbursement for time and travel

Ask your doctor for more information or contact our clinic to see if you may be eligible to participate.


Participating locations: Jordan River Family Medicine

High Cholesterol: Healthy Choices When Eating Out

Many restaurants offer delicious, low-fat, low-cholesterol meals. These tips will help you make eating out healthy and enjoyable.

Before You Order

  • If you are familiar with the menu, decide what to order before entering the restaurant. This tactic will help you avoid any tempting      foods that may not be as healthy.
  • If you are trying a new restaurant, take time to study the menu in order to avoid making unhealthy decisions.
  • Have the server remove temptations (such as the breadbasket) from the table.
  • Drink two full glasses of water before your food arrives.
  • Avoid foods described in the following way: buttery, buttered, fried, pan-fried, creamed, escalloped, au gratin (with cheese), or a la mode (with ice cream).
  • If you do eat bread before your meal, choose Melba toast or whole-grain rolls without butter or margarine.

When You Order

  • Order foods that are steamed, broiled, grilled, stir-fried, or roasted.
  • Order potatoes baked, boiled, or roasted instead of fried. Ask the server to leave off the butter and sour cream.
  • Order first so that you will not be influenced by other’s choices.
  • For appetizers, order broth-based soups such as minestrone or gazpacho instead of creamy soups or fried finger foods.
  • Choose seafood, chicken, or lean red meat rather than fatty or processed meats; remove all visible fat from any meat.
  • Ask for steamed vegetables instead of fries.
  • Ask for the sauces and dressings on the side so you can control how much you eat.
  • Ask the server about ingredients or preparation methods for the dishes you’re not familiar with.
  • For dessert, order sorbet or fresh, seasonal fruit without whipped cream or a topping.

For more from this website, please click on the link:

About this study:

  • For ages 18-80
  • 7 visits over 40 weeks

Please contact our participating location for more information!


Participating Locations: Foothill Family Clinic South

What are the signs, symptoms and potential health problems of HPV?

Most people with HPV do not develop symptoms or health problems from it. In 90% of cases, the body’s immune system clears HPV naturally within two years. But, sometimes, HPV infections are not cleared and can cause:

  • Genital warts
  • Rarely, warts in the throat — a condition called recurrent respiratory papillomatosis, or RRP. When this occurs in children it is called      juvenile-onset RRP (JORRP).
  • Cervical cancer and other, less common but serious cancers, including cancers of the vulva, vagina, penis, anus, and oropharynx (back of throat including base of tongue and tonsils).

The types of HPV that can cause genital warts are not the same as the types that can cause cancers. There is no way to know which people who get HPV will go on to develop cancer or other health problems.

HPV Can Happen To Anyone

Consider volunteering for a clinical research study of an investigational HPV vaccine.

Human Papillomavirus  (HPV) is the most common sexually transmitted infection. If it’s left untreated, some types of HPV can cause genital warts and cancer.

This clinical study is evaluating an investigational HPV vaccine. You may be able to join this study if you are healthy and:

  • Between 16 and 26 years old
  • Not sexually active or have had 4 or fewer sexual partners
  • Have not already received an HPV vaccine

Before you decide to participate, the study staff will explain the study risks and answer any questions you may have.

The study vaccine and all study-related tests and procedures will be provided at no cost. Volunteers may be paid for their time and travel expenses.

Call for more information or to volunteer!


Participating locations: Foothill Family Clinic, Foothill Family Clinic South, and Jordan River Family Medicine

What are the symptoms of the flu?

Flu symptoms include:

  • A 100oF or higher fever or feeling feverish (not everyone with the flu has a fever)
  • A cough and/or sore throat
  • A runny or stuffy nose
  • Headaches and/or body aches
  • Chills
  • Fatigue
  • Nausea, vomiting, and/or diarrhea (most common in children)

For more from this website, please follow the link:

  • Ages 18-70
  • MUST ENROLL IN STUDY WITHIN 48 HOURS OF ONSET. Please contact a participating site IMMEDIATELY when flu-like symptoms begin!


Participating locations: Foothill Family Clinic and Foothill Family Clinic South

Meningococcal meningitis

Causes, incidence, and risk factors

Meningococcal meningitis is caused by the bacteria Neisseria meningitidis (also known as meningococcus).

Most cases of meningococcal meningitis occur in children and adolescents. Meningococcus is the most common cause of bacterial meningitis in children and the second most common cause of bacterial meningitis in adults.

The infection occurs more often in winter or spring. It may cause local epidemics at boarding schools, college dormitories, or military bases.

Risk factors include recent exposure to meningococcal meningitis and a recent upper respiratory infection.


Symptoms usually come on quickly, and may include:

Other symptoms that can occur with this disease:

  • Agitation
  • Bulging fontanelles
  • Decreased consciousness
  • Poor feeding or irritability in children
  • Rapid breathing
  • Unusual posture with the head and neck arched backwards (opisthotonos)

For more from this article, please click on the link:


Participating locations: Foothill Family Clinic, Foothill Family Clinic South and Jordan River Family Medicine

What is meningococcal disease type B (MnB)?

Meningococcal disease type B (MnB) is caused by a certain type of bacteria that can make your child very sick. No vaccine to prevent MnB is currently available.

Your child (ages 10-12) may be eligible to take part in a clinical trial to test an investigational vaccine for MnB.


Participating locations: Foothill Family Clinic

We are only looking for those with Type 2 Diabetes at this point in the study

Research Study of a Hepatitis B Vaccine

In Adults 20 years of age and older with or without Type 2 Diabetes

What is this study about? Are you interested?

This study will test how the body responds to a hepatitis B vaccine for adults with or without type 2 diabetes.

  • You may join this study if:
  • You are 20 years of age or older
  • Within the past 5 years, you have had type 2 diabetes OR never had diabetes
  • You have never had a hepatitis B vaccine
  • You have never had hepatitis B infection
  • The study team will tell you what else is needed to join this study


Participating locations: Foothill Family Clinic


The symptoms of celiac disease can be different from person to person. This is part of the reason why the diagnosis is not always made right away. For example, one person may have constipation, a second may have diarrhea, and a third may have no problem with stools.

Gastrointestinal symptoms include:

Because the intestines do not absorb many important vitamins, minerals, and other parts of food, the following symptoms may start over time:

  • Bruising easily
  • Depression or anxiety
  • Fatigue
  • Growthdelay in children
  • Hair loss
  • Itchy skin (dermatitis herpetiformis)
  • Missed menstrual periods
  • Mouth ulcers
  • Muscle cramps and joint pain
  • Nosebleeds
  • Seizures
  • Tingling or numbness in the hands or feet
  • Unexplained short height

Children with celiac disease may have:

  • Defects in the tooth enamel and changes in tooth color
  • Delayed puberty
  • Diarrhea, constipation, fatty or foul-smelling stools, nausea, or vomiting
  • Irritable and fussy behavior
  • Poor weight gain
  • Slowed growth and shorter than normal height for their age

For more from this website, please click on the link:

Do you or someone you know have Celiac Disease?

Follow a Gluten-free diet?

Still experiencing symptoms when exposed to gluten?

Interested in Celiac Research?

Alba Therapeutics is sponsoring a clinical trial locally for Celiac Disease. The purpose of the research study is to look at how effective and safe an investigational medication is when it is given to subjects who have celiac disease. The study will include people who have been diagnosed with celiac disease and have been on a gluten-free diet for 12 months or more before study entry.

You may qualify for the study if you:

  • Are between the ages of 18 and 75 and have been diagnosed with celiac disease
  • Have biopsy proven celiac disease and positive serology test results for 12 months or more before study entry
  • Have been on a gluten-free diet for 12 months or more before study entry
  • Are still experiencing symptoms when exposed to gluten
  • Have positive serum anti-tTG (IgA or IgG) or DGP (IgA or IgG) antibodies atscreening
  • Are willing to maintain your current diet for the duration of the study
  • Satisfy other inclusion criteria

To participate in a survey to determine whether or not you qualify and to connect to a study site near you, call Research at a participating location.


Participating locations: Foothill Family Clinic South

Swimmer’s ear (otitis externa) is an inflammation and infection of the ear canal. It occurs when the protective film that covers the ear canal (lipid layer) is removed. This causes the ear canal to look red and swollen. The ear canal may be narrower than normal and is tender when the outside of the ear is gently pulled up and back.

Swimmer’s ear may develop when water, sand, dirt, or other debris gets into the ear canal. Since it often occurs when excess water enters the ear canal, a common name for this inflammation is “swimmer’s ear.” If you have had swimmer’s ear in the past, you are more likely to get it again.

A rare but serious infection called malignant external otitis can develop if bacteria invade the bones inside the ear canal and spread to the base of the skull. Not many people get this infection-it is mainly seen in older adults who also have diabetes, people who have HIV, and children who have impaired immune systems-but it can be fatal. Symptoms include ear pain with sudden facial paralysis, hoarseness, and throat pain. Antibiotics are used to treat this infection.

Other causes of inflammation or infection of the ear canal include:

  • Allergies.
  • Bony overgrowths in the ear canal called exostoses.
  • Bubble baths, soaps, and shampoos.
  • Cleaning the ear canal harshly or with a sharp object.
  • Headphones inserted into the ear.
  • Scratching the ear canal with a cotton swab, bobby pin, fingernail, or other sharp object.
  • Skin problems, such as eczema, psoriasis, or seborrhea.
  • Sweating.

Swimmer’s ear is more likely if you have a very narrow or hairy ear canal, live in a warm, humid climate, have impacted earwax, or have had a head injury that also injured your ear.

Symptoms can include itching, pain, and a feeling of fullness in the ear. Your ear canal may be swollen. You may have moderate to severe pain, drainage, or hearing loss. Unlike a middle ear infection (acute otitis media), the pain is worse when you chew, press on the “tag” in front of the ear, or wiggle your earlobe.

You don’t have to be a swimmer to get swimmer’s ear.

If you are experiencing pain, itching or swelling of the outer ear, you may have a type of ear infection called acute otitis externa (AOE), also known as swimmer’s ear. While swimmer’s ear is most commonly caused by swimming, it can also occur from the use of hearing aids, headphones (or “earbuds”) and various types of hearing protection.

Local doctors in your area are conducting a research study for effectiveness of investigational antibiotic drops for acute otitis externa (AOE). Individuals 6 months of age or older with swimmer’s ear may be eligible to participate.

Visit our website for more information:


Participating locations: Foothill Family Clinic, Foothill Family Clinic South, and Jordan River Family Medicine

Migraine in Children

Migraine is a common disorder in children. Estimates indicate that 3.5-5% of all children will experience recurrent headaches consistent with migraine. As in adults, most children (approximately 60%) have migraine without aura. Approximately 18% have only migraine with aura, 13% have both, and 5% experience only aura.

Migraines are incapacitating, throbbing headaches frequently located in the temples or frontal head regions. In children, the headaches are often bilateral (frontotemple) and may be nonthrobbing. Aura is infrequent prior to age 8 years. During the migraine episode, the child often looks ill and pale. Nausea and vomiting are frequent, particularly in young children. Patients avoid light (photophobia), noise (phonophobia), strong odors, and movement. Relief typically follows sleep.

Initial evaluation focuses on excluding other conditions. Management consists of identifying triggering factors, providing pain relief, and considering prophylaxis.

Conditions that are relatively common in the pediatric population and are thought to be variations and/or precursors of migraine include the following:

  • Benign paroxysmal vertigo
  • Cyclic vomiting
  • Paroxysmal torticollis
  • Transient global amnesia – Rare in children
  • Acute confusional migraine

For more from this website, please follow the link:

Trial of Evaluation and Efficacy of Nasal spray for ZOMIG®

Does your child experience migraine headaches? If the answer to this question is yes, and your child is 12-17 years of age, and experiences two or more migraine headaches a month, he or she may be eligible to join a clinical research study looking at an investigational treatment for migraine headaches.

The study will involve 3-4 visits to our clinic. Your child would be given a nasal spray containing study medication to take when a migraine headache occurs.

For more information, please contact Research